[3.27] 40+ million DPS perma-flask Poisonous Concoction | Trickster/Pathfinder/Deadeye
" The Deadeye version uses Nature's Adrenaline Forbidden Flesh/Flame jewels to essentially steal the Pathfinder flask charge ascendency. If you don't have those, you will struggle with flask charges. Make sure you are taking the other flask nodes, especially Replenishing Remedies. The Soul of Ryslatha Pantheon also helps, as does the +1 charge every 3 seconds Flask Mastery. It is technically possible to have permanent flasks on the Deadeye version just like the Pathfinder version because of those jewels, but you have to spec into all the necessary flask nodes. I'm using 2xLife Flasks to double the benefit of flask nodes, and I never run out of life while mapping - though I will if I spam attack continuously for too long when there aren't enough mobs dying. There's not usually any need to do that, though. PCoB hits so often you can take small breaks to give your life flasks a chance to recharge from all the kills. If you have high density maps, or are doing Harbingers for example, your life flasks will just never empty. You can also put "Chance to gain a flask charge when you deal a critical hit" on your life flasks to make certain, but it's honestly overkill and blocks the important "Increased Amount Recovered" mod, which gives us the big damage. Mind you, you've given me the idea to try this as I'm way overcapped on damage. At endgame because our damage is so high now we are at poison cap even without life flasks, so it shouldn't be a problem doing normal content. It's on the Uber bosses that life flasks begin to matter. Poison damage will feel a bit slow if you're used to hit builds, but you can take advantage of that by hitting and running as if things are already dead - which they will be in a few seconds. It can work in your favour as it allows you to load up damage when you can, and then move to avoid mechanics/attacks. You're no longer attacking but your poison is still doing work. It's a pretty cruisy playstyle once you get used to it. There are nodes that increase the rate of poison damage - e.g. Dirty Techniques - but I've never really noticed much of a difference. Last edited by t0lkien#7048 on Nov 15, 2025, 2:15:15 AM
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Awesome guide! I've successfully used it for the 3.27 league with slight/minimal variation with Pathfinder ascendancy.
Here's the PoB in case anyone is interested: https://pobb.in/4xXaFlNtcD90 Still running for endgame gear (+2 socketed projectile gem Replica's Farrul Fur is still missing as well as +2% increased mana reservation efficiency light of meaning and unnatural instincts) but it works amazingly well as is and the total budget spent so far has been in the realm of totally doable 300 divine orbs. 300k EHP 40M+ DPS Note: I personally preferred to move away of Vaal skills and to keep a couple nodes for life/mana leech; also to use a +#% elemental resistances implicit on the shield to be able to cap resistances without the usage of tattoos, and I also enabled the usage of Tempest Shield. That way I was able to reach 300k EHP without relying in perma flask (although perma flask is also enabled in this variation). The result is slightly less DPS (that is capped anyway) and a far cheaper end game build that is currently only missing the utmost rarest and more expensive unique variations. Thanks @t0lkien I've been really enjoying this build (is a favorite now)! |
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" Welcome, and you're welcome! You're not the first person to suggest Tempest Shield, and it's an interesting choice. I may look at it again down the line. For this league I went with Deadeye and I think it's my favourite ascendency for the build now. I tend to trade all other things for movement speed where I can without gimping myself, and this league I've been flying. I've found the league itself a little dull, but the build has been really soliid. Last edited by t0lkien#7048 on Nov 26, 2025, 12:56:09 AM
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As always, wonderful build for pcoc you have here. It's been great following it for another league! Thanks for sticking with it each league for all of us pcoc players, we love having you to help us out.
https://pobb.in/_Y3haIZVbm6h |
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