Path of Exile (not responding)

Quite often, the game does not respond in a variety of situations. Sometimes this happens during a large number of mobs on the screen, but more often it happens in cities and at fairly random moments. What can be done? What data should I send for evaluation?

Processor Intel(R) Core(TM) i5-9600K CPU @ 3.70GHz 3.70 GHz
RAM 24,0 ГБ
Graphics card MSI GeForce GTX 1660 SUPER GAMING X

Could you provide a more detailed description of what happens?

You say the game stops responding - what happens next? Does it resume accepting user input and re-enter a normal state? Does it abruptly close silently? Does it stay like that indefinitely until you choose to close the program?