For Those Having Trouble with Crashes

https://steamcommunity.com/app/238960/discussions/0/4509876948603653559/

Go to OPTIONS-->GRAPHICS-->scroll down to bottom under ADVANCED SETTINGS and find ENGINE MULTI-THREADING and DISABLE it. Click SAVE then exit the game and delete your shader caches under Users->Appdata->Roaming->PathofExile.

Hope this helps.