Pathofexile.exe not responding over and over

Never have I ever had this problem prior this league until day 1 of this league starting from the minute I logged on to my new character. Sometimes I'll get it 6-7 times in a row while trying to log back in, and other times it'll just happen randomly while in a map or loading into a new zone/town. It's most of the time happening while trying to login, but it still will happen at random while just playing the game.

I've checked my PC and nothing seems to be out of the ordinary. And this is the only time I have experienced this from any other program/game I run.

Any ideas? I've re installed. Settings are all cranked to minimum. But that's the thing, no settings have changed from the multitude of leagues in the past.