Hard to pick up items and interact with objects

I have to click items multiple times to pick them up, same with interacting with objects, because instead of picking-up an item I move to its location (literally). Have to hold Shift and left-click things. Blighted map was real messy:(

I have movement on left mouse button. Key pickup disabled.
Feels like movement takes priority over item-pickup and objects interaction.

Problems started after Mirage league launch. Probably as a result of this QOL changes - click shrine instead of attacking monsters.

Same here
Maps are taking longer now, imagine someone with this problem that plays harbinger farming LOL