CPU Deadlocks

My current CPU is a AMD Ryzen 5 7600X3D and the game was running fine on Vulkan renderer before the midleague "Improvements to the Fate of the Vaal League" update. Now whenever I enter maps my game constantly hard freezes my entire computer (seemingly more commonly when large calculations are happening like lots of loot dropping) but my telemetrics never indicate any spikes in cpu load. I have tried a large variety of fixes like disabling CPU 0, clearing my shader caches, swapping renderers, and rolling back Windows updates and Nvidia drivers. Another thing to make note of is the game will occasionally run without any issues for a few hours; the processes running in the background on my machine have remained consistent, and the deadlocking seems to be pretty random.
Last bumped on Dec 21, 2025, 12:21:08 PM
Believe I am having the same issue you are having on a 5900X since the improvement update. Game ran fine before then. Now my game randomly freezes and if I click on the screen it gives me the "POE2 isn't responding, close program/wait for program to respond" pop-up box.

If I click "wait to respond" or just dont touch screen after the freeze, after about 15seconds the instance will reload and let me continue.

I've had it happen in maps fighting mobs/boss, sitting in the atlas, sitting in hideout.

Tried different renderers/different NVIDIA updates to no success.

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