We need more NPCs reacting to particular actions and events.

Trialmaster has one of the funniest lines when he comments on our win streaks and misfortunes. A sailor dude during campaign that complains about us leaving before he could finish speakig was hilarious. I think we need more interactions like that in the game.

Let some NPC in our hideout (or in town during campaign) to say something when you're using salvage or reforging bench, or opening a new portal, or slamming that vaal orb, or trying your luck with recombinator, or logging in the next day, and definitely when you revive (maybe even consider the way you died to choose a proper remark).

Some NPCs can be cruel and merciless with their jokes, while other can try to comfort and cheer you up. Or they can have little banter between each other, similar to heist guys back in PoE1.

And while we're at it, I want an NPC to throw people out of my hideout when they are finished with trading but hanging around for too long. And I want it to be Viper Napuatzi.

They have done it a bit with the Mercs in Merc league as well. Might be something they are looking at implementing more. Kind of thing where if it is done well, it improves the game, but sometimes can miss the mark. Example, POE 1, Rog implies you've got a great item when it is not.