Can't attack ennemies on my invoker on POE 2

It's been a day that i can't attack ennemies in poe 2. When i click on mobsnothing append, but when i go to my chest or I select an item, my mouse work... The keybind of the 1st ability is in grey, i can't bind a keybind. I delete and download again, and nothing change. I played my second caracter, and on this caracter i can attack mobs, and I can assign keybin for my 1st ability