Sound randomly cuts out during gameplay

As the title says. I use the RIG 500 by Plantronics. I can fix the issue by going to the options menu and changing the audio output from my headphones to my computer's default (speakers) and then changing it back to my headphones. However, the issue comes back anytime after 30 minutes to an hour.

PoE is the only game where I experience this issue; watching videos online or playing another game through my headphones give no issues.